I think you will find that the most common reason why cats lose hair is because of over grooming. The question that follows is, "why is the cat over grooming?".
Perhaps the most common reason why cats over groom is because of stress. Stress can be caused by a number of situations and events and it would be impossible to list them all here but perhaps the most typical would be stress caused by other cats in a multi-cat household. Another cause of stress would be the owner being away too much causing separation anxiety. It is up to the owner to figure out what is causing the stress. This will take a certain amount of observation of the behaviour of the cat or cats in their home and should become quite apparent very quickly what is going on.
After stress, the obvious reason why cats over groom is because their skin feels itchy. This leads to another secondary question namely why does the skin feel itchy? The most common reason for this is probably the flea bite allergy. Secondary to that would be irritation caused by other external parasites. After that I would suggest that either airborne or ingested allergens are the cause of the cat's skin feeling itchy.
In conclusion, therefore, if a cat is losing hair in a symmetrical way in easy accessible places then it is due to over grooming due to stress. If there are areas that are missing hair and the skin can be seen to have inflamed areas in it then this could quite likely be the flea bite allergy.
The cat flea is probably the most common cause of cat health problems and it is very important that cat owners ensure that the cat is free of fleas which obviously means for a high level of vigilance especially if the cat goes outside a lot.
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